Onset Dermatologics Launches Patented Aurstat® Anti-Itch Hydrogel 225mL

Cumberland, R.I. (May 6, 2013) – Onset Dermatologics, a PreCision Dermatology Company and a leader in developing and commercializing novel, prescription products for improving skin health, today announced the availability of Aurstat® Anti-Itch Hydrogel. Aurstat® is a treatment for itch, including itch related to atopic dermatitis. Atopic dermatitis is also called eczema. Aurstat® contains HOCl (hypochlorous acid) as a preservative. Atopic dermatitis is a common skin disorder characterized by red, inflamed, dry, cracked, itching skin and is often called the "itch that rashes”. Itching, which is sometimes intense, may start even before the rash appears. Atopic dermatitis is most prevalent in children, with approximately 13 percent of all children in the United States suffering from this chronic disease 1.

"Itch is a very uncomfortable symptom of atopic dermatitis, arguably worse than the sensation of pain conducted by the same nerve fibers. Thus, it is often the chief complaint of these patients due to its impact on their quality of life. Additionally, it is pivotally important to control the itch of atopic dermatitis in order to reduce the scratching that can worsen the severity of atopic lesions,” noted Brian Berman, MD, PhD, FAAD, Co-Director Center for Clinical and Cosmetic Research, Aventura, FL, and Voluntary Professor of Dermatology and Cutaneous Surgery, Miller School of Medicine, University of Miami. "HOCl is a key component of bleach baths, a traditional treatment for atopic dermatitis. Though the mechanism of action is unknown, dermatologists have observed that bleach baths reduce the severity of atopic dermatitis symptoms, including itch.”

Aurstat® was engineered to soothe itching, burning, and pain of atopic dermatitis and various dermatoses. The patented hydrogel formulation is alcohol free, fragrance free, non-irritating, non-sensitizing, and non-cytotoxic. Aurstat® is safe to use on the face and around the eyes. The product has no age restrictions.

"Dermatologists have expressed a need for new safe treatments for the itch that causes so much suffering in their patients. Aurstat Hydrogel is a non-steroidal treatment that addresses that need,” said Robert Moccia, President, Onset Dermatologics. "We are committed to providing thoughtfully engineered products to help dermatologists improve outcomes in their atopic dermatitis patients.”

Aurstat® Anti-Itch Hydrogel 225mL is now available in the U.S. by prescription only.

About Onset Dermatologics

Headquartered in Cumberland RI, Onset Dermatologics LLC, a subsidiary of PreCision Dermatology, Inc., is a fully-integrated prescription dermatology company with a mission to deliver innovative therapies to dermatologists and their patients. In addition to Aurstat®, Onset Dermatologics markets the prescription brands Locoid®, HylatopicPlus®, Tretin-X®, Minocin®, and Clarifoam®EF to dermatologists and their allied healthcare providers. Onset is expanding rapidly through internally generated innovation, acquisitions, in-licensing, and co-marketing opportunities. For additional information, visit www.onsetdermatologics.com.

Important Safety Information for Aurstat® Anti-Itch Hydrogel

Aurstat® Anti-Itch Hydrogel is indicated for the management and relief of pain, burning and itching experienced with various dermatoses, including atopic dermatitis, allergic contact dermatitis and radiation dermatitis, as well as for the relief of pain from first and second degree burns, and aids to relieve dry waxy skin by maintaining a moist wound and skin environment. A moist wound and skin environment is beneficial to the healing process.

1 Silverberg JI, Hanifin J, Simpson EL. Climatic factors are associated with childhood eczema prevalence in the United States. J Invest Dermatol. 2013. doi: 10.1038/jid.2013.19; 10.1038/jid.2013.19.